Clitoral blood flow after use of gel containing L-arginine and L-citrulline. Turnera diffusa Wild (Turneraceae) recovers sexual behavior in sexually exhausted males. Journal of Ethnopharmacology, 123(3), 423–429. Hypoactive Sexual Desire Disorder: International Society for the Study of Women's Sexual Health (ISSWSH) Expert Consensus Panel Review. Mayo Clinic Proceedings, 92(1), 114–128. Flibanserin for Premenopausal Hypoactive Sexual Desire Disorder: Pooled Analysis of Clinical Trials. Journal of Women's Health (2002), 28(6), 769–777. Melanocortin 4 receptor agonism enhances sexual brain processing in women with hypoactive sexual desire disorder. Peripheral Female Genital Arousal as Assessed by Thermography Following Topical Genital Application of Alprostadil vs Placebo Arousal Gel: A Proof-of-Principle Study Without Visual Sexual Stimulation. Effect of Diindolylmethane on Estrogen-related Hormones, Metabolites and Tamoxifen Metabolism: Results of a Randomized, Placebo-controlled Trial. Cancer Epidemiology Biomarkers & Prevention 1, 26(3), 435. Flibanserin (Addyi): The First FDA-Approved Treatment for Female Sexual Interest/Arousal Disorder in Premenopausal Women. Role of Nitric Oxide in the Cardiovascular and Renal Systems. International Journal of Molecular Sciences, 19(9), 2605. Systematic review and meta-analysis of phosphodiesterase type 5 inhibitors for the treatment of female sexual dysfunction. International Journal of Gynecology & Obstetrics, 133(2), 139-145. Effect of long-term intranasal oxytocin on sexual dysfunction in premenopausal and postmenopausal women: a randomized trial. (308) Oxytocin Troches as an Adjunctive Intervention to Conventional Testosterone and Erectile Dysfunction Medication for Men with Sexuality Concerns. The Journal of Sexual Medicine, 20(Supplement_1). Tadalafil once daily: Narrative review of a treatment option for female sexual dysfunctions (FSD) in midlife and older women.
- Black cohosh is sometimes used to increase libido temporarily.
- Yohimbine is a supplement linked to improved blood flow and desire.
- Maca root is popular for boosting energy and sexual desire swiftly.
- Ginkgo biloba is thought to improve circulation and arousal quickly.
- Damiana herb is traditionally used as an aphrodisiac for immediate effect.
- Horny goat weed may support increased arousal within an hour.
Tadalafil reversal of sexual dysfunction caused by serotonin enhancing medications in women. Journal of Sex & Marital Therapy, 32(1), 1–3.
What women are saying
The effect of topically applied vasoactive agents and testosterone versus testosterone in the treatment of erectile dysfunction in aged men with low sexual interest. International Journal of Impotence Research, cenforce100 13(2), 93–99. Chemical composition, olfactory evaluation and antioxidant effects of essential oil from Mentha x piperita. Natural Product Communications, 4(8), 1107–1112. Randomised controlled trial of the effects of L-ornithine on stress markers and sleep quality in healthy workers. Tadalafil 5 mg Daily Treatment for Type 1 Diabetic Premenopausal Women Affected by Sexual Genital Arousal Disorder. The Journal of Sexual Medicine, 9(8), 2057-2065. Influence of a Specialized Trigonella foenum-graecum Seed Extract (Libifem), on Testosterone, Estradiol and Sexual Function in Healthy Menstruating Women, a Randomised Placebo Controlled Study. Safety and influence of a novel extract of fenugreek on healthy young women: A randomized, double-blinded, placebo-controlled study. Evaluation of aphrodisiac activity of ethanol extract of Ganoderma lucidum in male Wistar rats.
- Sildenafil (Viagra) can increase blood flow, potentially boosting arousal.
- Tadalafil (Cialis) works longer, providing hours of improved mood and desire.
- Levitra (Vardenafil) may help enhance sensitivity and desire quickly.
- Injectables like alprostadil increase blood flow instantly for arousal.
- Herbal supplements like ginseng are believed to boost energy and mood.
- OTC products claim to enhance libido through various ingredients.
Translational Andrology and Urology, 11(7), 982. Guaraná's Journey from Regional Tonic to Aphrodisiac and Global Energy Drink. Evidence-Based Complementary and Alternative Medicine: ECAM, 7(3), 279. Effectiveness sex pills for women of guaraná (Paullinia cupana) for postradiation fatigue and depression: results of a pilot double-blind randomized study. Journal of Alternative and Complementary Medicine (New York, N.Y.), 15(4), 431–433. Effects of a commercial product containing guaraná on psychological well-being, anxiety and mood: A single-blind, placebo-controlled study in healthy subjects. Journal of Negative Results in Biomedicine, 12, 9. (023) The Acute Effect of Caffeine on Genital Arousal in Women: A Pilot Study.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Professional | 40mg | 60 + 2 Pills | 262.32€ 249.83€ | |
| Kamagra Soft Tabs | 100mg | 272 + 12 Pills | 593.42€ 565.16€ | |
| Kamagra 100 mg | 100 mg | 180 + 6 Pills | 436.79€ 415.99€ | |
| Tadalista Super Active | 20mg | 270 + 30 Pills | 661.49€ 629.99€ | |
| Levitra Generic | 40mg | 60 + 4 Pills | 162.37€ 154.64€ | |
| Kamagra Gold | 100 mg | 120 + 6 Pills | 330.74€ 314.99€ | |
| Kamagra Soft Tabs | 100mg | 12 Pills | 57.55€ 54.81€ | |
| Kamagra Gold | 50 mg | 12 Pills | 47.30€ 45.05€ | |
| Viagra Professional | 100mg | 360 + 6 Pills | 527.09€ 501.99€ | |
| Levitra Professional | 20mg | 10 Pills | 62.37€ 59.40€ | |
| Cialis Generic | 2.5mg | 90 + 6 Pills | 112.43€ 107.08€ | |
| Viagra Generic | 100mg | 60 + 4 Pills | 96.36€ 91.77€ |
The Journal of Sexual Medicine, 20(Supplement_2). Crocus sativus (saffron) in the treatment of female sexual dysfunction: A three-center, double-blind, randomized, and placebo-controlled clinical trial. Saffron for treatment of fluoxetine-induced sexual dysfunction in women: Randomized double-blind placebo-controlled study.
9. Probiotics
Evaluation of Dietary Niacin and New-Onset Hypertension Among Chinese Adults. Hop extracts and hop substances in treatment of menopausal complaints. Hops for Menopausal Vasomotor Symptoms: Mechanisms of Action. Journal of Traditional and Complementary Medicine, 2(4), 331-339. Efficacy of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial.
Consult A Professional
Menopause (New York, N.Y.), 23(11), 1252–1256. A systematic review of clinical trials on Ginkgo (Ginkgo biloba) effectiveness on sexual function and its safety. Journal of ethnopharmacology, 145(3), 715–721. Capsaicinoids Modulating Cardiometabolic Syndrome Risk Factors: Current Perspectives. The effect of melatonin on the sexual function among postmenopausal women: A randomized placebo-controlled trial. Human Psychopharmacology: Clinical and Experimental, 28(1), 54-60. Tribulus terrestris for treatment of sexual dysfunction in women: Randomized double-blind placebo-controlled study. DARU Journal of Pharmaceutical Sciences, 22(1), 40.
Real Science. Real Results.
Nursing and Midwifery Studies, 6(4), 149. Understanding Unapproved Use of Approved Drugs "Off Label". Physiologic Measures of Sexual Function in Women: A Review. Topical Pentoxifylline for Pressure Injury Prevention: A Call for Clinical Research. Advances in skin & Wound Care, 32(11), 486. Tribulus Terrestris for Female Sexual Dysfunction: A Systematic Review. Tribulus terrestris and female reproductive system health: A comprehensive review. Bioavailability enhancers of herbal origin: An overview.
Further information
Effects of nine weeks L-Carnitine supplementation on exercise performance, anaerobic power, and exercise-induced oxidative stress in resistance-trained males. Journal of Exercise Nutrition & Biochemistry, 22(4), 7-19. Topics in Current Chemistry, 328, 155–240. Seminal plasma magnesium and premature ejaculation: a case-control study. The Role of Magnesium in Hypertension and Cardiovascular Disease.
Ingredients Matter
The Journal of Clinical Hypertension, 13(11), 843-847. Effect of Zinc on Testosterone Levels and Sexual Function of Postmenopausal Women: A Randomized Controlled Trial. Journal of Sex & Marital Therapy, 47(8), 804–813. BIOCHEMISTRY OF MOBILE ZINC AND NITRIC OXIDE REVEALED BY FLUORESCENT SENSORS. Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review. Asian Pacific Journal of Tropical Biomedicine, 3(4), 253. Fenugreek, A Potent Hypoglycaemic Herb Can Cause Central Hypothyroidism Via Leptin - A Threat To Diabetes Phytotherapy.
The bottom line
Pharmacy: Journal of Pharmacy Education and Practice, 9(2). Vyleesi Prices, Coupons and Patient Assistance Programs. Endothelial Nitric Oxide Synthase Regulation in Female Genital Tract Structures. The Journal of Sexual Medicine, 6, 247-253. Yes, you can have better sex in midlife and in the years beyond.
A note about sex and gender
Testosterone therapy in women: Does it boost sex drive? Treatment of Hypoactive Sexual Desire Disorder Among Women: General Considerations and Pharmacological Options. Focus: Journal of Life Long Learning in Psychiatry, 19(1), 39-45. Integrative Medicine (Fourth Edition), 592-599.e2. Oral L-citrulline supplementation improves erection hardness in men with mild erectile dysfunction. Experimental and Clinical Endocrinology & Diabetes: Official Journal, German Society of Endocrinology [and] German Diabetes Association, 125(7), 441–448. Phytoestrogenic effect of fenugreek seed extract helps in ameliorating the leg pain and vasomotor symptoms in postmenopausal women: A randomized, double-blinded, placebo-controlled study. Exploring the Potential of Saffron as a Therapeutic Agent in Depression Treatment: A Comparative Review. The Yale Journal of Biology and Medicine, 97(3), 365. Addyi helps balance neurotransmitters like dopamine, serotonin, and norepinephrine to support sexual desire. The exact way Addyi works is unknown. ADDYI was studied in four 6-month clinical trials in more than 3,200 women with low sexual desire, of whom 902 were postmenopausal and under 65. Participants were randomly assigned to receive ADDYI or a placebo. Researchers evaluated changes in the number of sexually satisfying events, desire, and stress due to frustrating low sexual desire.
Find out if treatment is right for you.
M., Parish, S. J., Simon, J. The International Society for the Study of Women's Sexual Health Process of Care for Management of Hypoactive Sexual Desire Disorder in Women. Mayo Clinic Proceedings, 93(4), 467–487. Female sexual dysfunction (FSD): Prevalence and impact on quality of life (QoL).
Is it safe?
Mayo Foundation for Medical Education and Research (MFMER). Icahn School of Medicine at Mount Sinai. 197 A Double-blind, Placebo-controlled, 2-Way Crossover Study Using Thermography to Assess the Pharmacodynamics of Sildenafil Cream, 3.6% in Healthy Women. The Journal of Sexual Medicine, 17(1), S69. Systematic Review of l-Arginine for the Treatment of Hypoactive Sexual Desire Disorder and Related Conditions in Women. Getting Addyi doesn’t have to be complicated or expensive. Patients with insurance coverage pay as little as $20 per month2.
- Some pills contain pheromones to attract sexual interest instantly.
- Certain vitamins, like B6 and B12, may improve mood and vitality quickly.
- Nitric oxide boosters can increase blood flow and arousal rapidly.
- Herbal stimulant blends are marketed for immediate mood enhancement.
- Quick-acting mood enhancers include L-arginine supplements.
- Aromatherapy sprays claim to set a sensual mood instantly.
Addyi is only $149/month through PHILRx, delivered free to your door, and their coupon is automatically applied. When brain chemicals fall out of balance, sexual desire can drop too. “Addyi helped me reconnect with my desire in a way that finally felt sustainable.” “After menopause, I thought losing desire was just something I had to accept.
| Pill Type | Common Side Effects | Serious Risks | Who Should Avoid |
|---|---|---|---|
| Synthetic pills | Headaches, flushes | Heart risks, priapism | Cardiac issues, hypertension |
| Herbal remedies | Nausea, dizziness | Allergic reactions | Pregnancy, allergies |
| Supplements | Digestive upset | Interactions with medications | Liver or kidney disease |
Addyi helped me realize I didn’t.” “For the first time in a long time, I feel more engaged and satisfied during sex, not distracted or checked out.” “I had no desire, I thought it was just me… something that happened as I got older. But then one of my girlfriends told me about Addyi. All I have to say is OMG… I wish I had learned about this sooner!” “Addyi helped me reconnect with my desire in a way I’d been missing for years.” “I used to dread going to bed with my husband because I was never in the mood… he thought it was his fault.
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