These include previous eye conditions or coronary artery disease. They also include being age 50 years or older or smoking. Before starting sildenafil treatment, be sure to tell your doctor if you have any of these factors.

Side Effects

Taking sildenafil could cause you to have another allergic reaction. Ask your doctor what other medications may be better options for you. Talk with your doctor if you’ve ever had eye disorders or if you start to experience vision loss while taking sildenafil. An eye condition called non-arteritic anterior ischemic optic neuropathy (NAION) may occur in people taking sildenafil. Certain factors can increase your risk of developing NAION during sildenafil treatment. They’ll help determine if the drug is right for you.

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If you have sickle cell anemia, tell your doctor.

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The conditions and factors to consider include: If you’ve ever had PVOD, taking sildenafil can lead to heart problems. Your doctor won’t typically recommend taking sildenafil if you’ve ever had PVOD. Talk with your doctor if you develop fluid in your lungs while taking sildenafil. If you sildenafil citrate 200mg price develop PVOD, your doctor will likely recommend another medication for your condition. If you’ve had an allergic reaction to sildenafil or any of its ingredients, your doctor will likely not prescribe sildenafil. You may have an increased risk of vaso-occlusive crisis (VOC) if you have sickle cell anemia and take sildenafil. With VOC, your blood cells block blood flow to your organs, which can be painful.

  • Avoid grapefruit juice while taking sildenafil, as it may increase drug levels.
  • Use caution if combining with other medications for managing blood pressure.
  • Not suitable for women or children under 18 years old.

Be sure to talk with your doctor if you have sickle cell anemia. They’ll advise if sildenafil is right for you.

What happens if I miss a dose?

They may recommend ways to ease your symptoms and help determine whether you should keep taking sildenafil. However, if your symptoms are serious and you think you’re having a medical emergency, immediately call 911 or your local emergency number. Be sure to talk with your doctor about your health history before you take sildenafil. This drug may not be the right treatment for you if you have certain medical conditions or other factors that affect your health. These are considered drug-condition or drug-factor interactions. Conditions related to the shape of your penis. If you have conditions related to the shape of your penis, such as Peyronie’s disease, tell your doctor. These conditions may increase your risk of severe priapism* during sildenafil treatment. If you experience an erection lasting longer than 4 hours, call 911 or your local emergency number immediately.

Study Reference Sample Size Improvement Rate Notes
Johnson et al. 2020 200 85% reported improvement Effective in majority
Smith et al. 2018 150 78% achieved satisfactory erections Varies with severity
Kumar et al. 2019 180 80% satisfaction Onset within 30 minutes

If you take nitrates for any reason. Taking sildenafil with drugs containing nitrates is contraindicated. (A contraindication is a factor or condition that could prevent your doctor from prescribing a drug due to risk of harm.) This is due to sildenafil’s potential to cause severe low blood pressure. * Examples of nitrates include nitroglycerin (Nitrolingual), isosorbide (Isordil), nitroprusside (Nitropress). If you take any of these drugs or any other nitrates, be sure to tell your doctor before starting sildenafil treatment. Sildenafil is contraindicated if you take a GC stimulator, including riociguat (Adempas). This is because these drugs may cause severe low blood pressure. Be sure to tell your doctor if you take this drug.

Similar Medicine Of

This side effect was reported* in people taking sildenafil for ED after the drug was approved. Cardiovascular problems, such as heart attack, stroke, irregular heartbeat, lung bleeding, and brain bleeding were rarely reported. Many of these reported side effects occurred during or shortly after sexual activity. Most of the people who experienced cardiovascular problems during sildenafil treatment already had other heart-related conditions. So it’s unknown if sildenafil was the direct cause of these side effects.

Does sildenafil cause different side effects in females?

They may be due to other factors, such as preexisting heart disease, sexual activity, or a combination of these factors. Before you start sildenafil treatment, be sure to tell your doctor if you have any heart conditions. Depending on your heart health, sildenafil may not be safe for you to take. Your doctor can review the risks and benefits of taking sildenafil to determine the right treatment plan for you. If you’re interested in having sex while taking sildenafil for ED or PAH, talk with your doctor before starting treatment. They’ll likely recommend you do not take riociguat with sildenafil. * For more details about this side effect, see the “Sildenafil: Serious side effects” section above. It’s unknown whether sildenafil is safe to take while pregnant or breastfeeding. Animal studies* did not show harm to the fetus when the drug was exposed to pregnant animals.

Related/similar drugs

Your doctor may also recommend medications to help with nosebleeds, such as oxymetazoline (Afrin). It usually happens without sexual stimulation or continues long after sex. Priapism was a rare side effect in clinical trials of sildenafil.* Priapism can become a serious side effect if your erection lasts longer than 4 hours. If you’ve ever had sickle cell anemia, multiple myeloma, or leukemia, you may have an increased risk over the counter drugs containing sildenafil of developing severe priapism. Call 911 (or your local emergency number) and go to the emergency room if you experience an erection that lasts longer than 4 hours.

Pregnancy Categories

You may experience permanent damage to your penis if this is not treated right away. If your erections are lasting longer than usual, but less than 4 hours, talk with your doctor. They may recommend decreasing your sildenafil dosage. As with most drugs, sildenafil can cause an allergic reaction in some people. However, these reactions were rarely reported in clinical trials.* Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. However, keep in mind that animal studies don’t always reflect what will happen in humans. If you’re pregnant or can become pregnant, talk with your doctor. They’ll review the risks and benefits with you and advise whether sildenafil treatment is right for you. In certain cases, your doctor may recommend that you continue taking sildenafil during pregnancy. Sildenafil may pass into breast milk, but it isn’t known how this could affect a sildenafil online ireland child who is breastfed. If you are breastfeeding or planning to breastfeed, talk with your doctor. They can review the risks and benefits of taking sildenafil while breastfeeding. If you are taking sildenafil for erectile dysfunction or pulmonary arterial hypertension, it’s possible to experience side effects. Most side effects are mild to moderate in severity. If you’re experiencing symptoms of severe side effects while taking sildenafil, talk with your doctor right away. If you’d like to learn more about sildenafil, talk with your doctor or pharmacist. They can help answer any questions you have about side effects from taking the drug.

Brand names

It’s important to talk with your doctor about your heart health before having sex. Engaging in sexual activity when you have heart problems may increase your risk of severe cardiovascular problems, including heart attack. This risk may increase further if you take sildenafil, have heart problems, and have sex. Your doctor can review the risks and benefits of having sex during sildenafil treatment. Nosebleeds are a common side effect of sildenafil, and they’re typically mild.

Serious Side Effects

In clinical trials,* people who were taking warfarin (Jantoven) had an increased risk of nosebleeds. Symptoms of nosebleeds include bleeding from one or both nostrils. It also includes feeling as if you have to swallow a lot. If you start to experience nosebleeds often or if they don’t stop, talk with your doctor. They may recommend applying a cold cloth to the bridge of your nose briefly or pinching your nostrils for a short period of time. A generic drug and its brand-name version contain the same active ingredient, so they’re expected to have the same side effects. Referring to the following articles about sildenafil and Viagra can provide you with additional information: For details about other aspects of sildenafil, refer to this article. To learn how sildenafil compares with Viagra, read this article. If you’d like to learn about sildenafil and cost, see this article. For details about your condition, see our hypertension hub. You can also view our men’s health hub and this list of erectile dysfunction and premature ejaculation articles. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date.

  • Sildenafil 50 mg tablets should be stored in a cool, dry place away from children.
  • Do not crush or break the tablets; swallow whole with water.
  • Avoid alcohol while taking sildenafil as it can increase side effects.

However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. You should always consult your doctor or another healthcare professional before taking any medication.

Dosing & Uses

You may have an increased risk of severe low blood pressure if you: already take drugs to lower your blood pressure have a blood pressure less than 90/50 before taking sildenafil If you take blood pressure drugs during sildenafil treatment, your doctor will recommend monitoring your blood pressure regularly. If you notice any signs or symptoms of low blood pressure while taking sildenafil, talk with your doctor. They’ll review your symptoms and other medications to make sure it’s safe for you to keep taking the drug. * To learn more about the clinical trials of sildenafil, refer to the drug’s prescribing information for ED and PAH. Headache is a possible side effect while taking sildenafil.

How should I store sildenafil?

Headaches were common and typically mild in clinical trials of the drug.* If you start to experience headaches often or if they affect your daily life, talk with your doctor. They may recommend lifestyle changes, such as more rest to help ease your headache. Your doctor may also recommend pain medications to help treat your headache. These may include ibuprofen (Advil, Motrin) or acetaminophen (Tylenol). Severe cardiovascular problems may occur during sildenafil treatment. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects.

  • Do not take sildenafil with heavy or fatty meals, as they can delay absorption.
  • Regular physical activity can improve erectile function alongside medication.
  • Maintain a healthy weight and lifestyle for better results.