DHEA, herbal will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
| Aspect | Description | Typical Dosage | Onset Time | Duration of Action |
|---|---|---|---|---|
| Vardenafil 5 mg | A medication used to treat erectile dysfunction | 5 mg | 30-60 min | Up to 4-5 hours |
| Pharmacological Class | Phosphodiesterase type 5 inhibitor | N/A | N/A | N/A |
| Brand Names | Levitra, Staxyn (dissolvable film) | N/A | N/A | N/A |
diltiazemdiltiazem will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Adverse Effects
Coadministration may increase PDE-5 inhibitor adverse effects including hypotension, syncope, visual changes, and prolonged erection; do not exceed vardenafil 2.5 mg q72hr. darunavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. dasatinibdasatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.dasatinib and vardenafil both increase QTc interval. dasatinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
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deferasiroxdeferasirox will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. deferasirox will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. degarelixdegarelix and vardenafil both increase QTc interval. degarelix and vardenafil both increase QTc interval. At the maximum recommended dose, deutetrabenazine does not prolong QT interval to a clinically relevant extent.
Mechanism of Action
Certain circumstances may increase risk of torsade de pointes and/or sudden death in association with drugs that prolong the QTc interval (eg, bradycardia, hypokalemia or hypomagnesemia, coadministration with other drugs that prolong QTc interval, presence of congenital QT prolongation). deutetrabenazine and vardenafil both increase QTc interval. dexamethasonedexamethasone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. dexamethasone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. DHEA, herbalDHEA, herbal will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors diltiazem will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dofetilidedofetilide increases toxicity of vardenafil by QTc interval.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Viagra Generic | 150mg | 270 + 10 Pills | 326.61€ 311.06€ | |
| Super Kamagra | 160 mg | 60 + 4 Pills | 342.71€ 326.39€ | |
| Cialis Professional | 20mg | 10 Pills | 48.29€ 45.99€ | |
| Cialis Generic | 40mg | 10 Pills | 37.79€ 35.99€ | |
| Kamagra Soft Tabs | 100 mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Cialis Generic | 5mg | 360 + 10 Pills | 268.08€ 255.31€ | |
| Cialis Generic | 5mg | 270 + 10 Pills | 205.81€ 196.01€ | |
| Cialis Generic | 20mg | 360 + 10 Pills | 427.34€ 406.99€ | |
| Levitra Soft Tabs | 20mg | 10 Pills | 52.27€ 49.78€ | |
| Kamagra | 100mg | 180 + 6 Pills | 436.79€ 415.99€ | |
| Viagra Generic | 100mg | 30 + 4 Pills | 60.91€ 58.01€ | |
| Super Kamagra | 160 mg | 8 Pills | 69.23€ 65.93€ | |
| Tadalista Super Active | 20mg | 10 Pills | 55.64€ 52.99€ | |
| Cialis Generic | 60mg | 20 Pills | 65.61€ 62.49€ | |
| Apcalis SX Oral Jelly | 20mg | 30 + 5 Sachets | 141.84€ 135.09€ | |
| Kamagra | 100mg | 84 + 6 Pills | 264.44€ 251.85€ |
dofetilide increases toxicity of vardenafil by QTc interval.
| Parameter | Value | Notes |
|---|---|---|
| Absorption Rate | Fast | Peak plasma concentration in ~1 hour |
| Bioavailability | Approximately 15% | Due to first-pass metabolism |
| Half-Life | About 4-5 hours | Time for plasma levels to reduce by half |
| Metabolism | Primarily hepatic via CYP3A4 | Liver enzyme responsible |
donepezildonepezil and vardenafil both increase QTc interval. dordavipronedordaviprone and vardenafil both increase QTc interval.
- Vardenafil 5 mg is available in tablet form for oral use.
- It is important to complete the full course unless advised otherwise.
- The medication’s effect can be delayed or reduced by certain foods.
- Regular medical follow-up enhances safe use.
- Patients should inform the doctor of all medications they are taking.
- Its efficacy can be reduced by smoking or excessive alcohol.
- Use with caution in elderly patients due to increased sensitivity.
- Label instructions should be carefully read before use.
- Over-the-counter use without consultation is discouraged.
- Vardenafil 5 mg does not protect against pregnancy or STDs.
- Maintain a healthy weight to improve medication effectiveness.
- Report any allergic reactions like rash or swelling immediately.
Increase the frequency of ECG and electrolyte monitoring. dordaviprone and vardenafil both increase QTc interval. doxepindoxepin and vardenafil both increase QTc interval.
| Interacting Drug | Effect on Vardenafil 5 mg | Recommendations |
|---|---|---|
| Nitrates | Severe hypotension risk | Avoid concurrent use |
| CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) | Increased Vardenafil levels | Reduce dose or avoid |
| Alpha-blockers | Potential for hypotension | Use with caution, monitor blood pressure |
| Grapefruit juice | Increases drug plasma concentration | Limit intake before dosing |
doxepin and vardenafil both increase QTc interval. dronedaronedronedarone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dronedarone will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Dosing & Uses
cortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. crizotinibcrizotinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Dose reduction may be needed for coadministered drugs that are predominantly metabolized by CYP3A. crizotinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. crofelemercrofelemer increases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Related treatment guides
Crofelemer has the potential to inhibit CYP3A4 at concentrations expected in the gut; unlikely to inhibit systemically because minimally absorbed. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors. crofelemer increases levels of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. cyclosporinecyclosporine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors cyclosporine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
What else should I know about vardenafil?
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors dabrafenibdabrafenib will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. dabrafenib will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. darifenacindarifenacin will increase the level or effect of vardenafil by affecting tadacip 20 tablet hepatic/intestinal enzyme CYP3A4 metabolism. darifenacin will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. darunavirdarunavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors duvelisibduvelisib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
How RedBox Rx can help
butalbitalbutalbital will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. butalbital will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. ceritinibceritinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors ceritinib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors chloramphenicolchloramphenicol will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
How do the side effects compare for vardenafil and tadalafil?
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors chloramphenicol will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors cimetidinecimetidine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. cimetidine will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. ECG monitoring is recommended, along with drugs that may prolong the QT interval. clarithromycinclarithromycin will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
What is vardenafil, and what is it used for?
Limit vardenafil dose to 2.5 mg/24 hr clozapineclozapine and vardenafil both increase QTc interval. clozapine and vardenafil both increase QTc interval. cobicistatcobicistat will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors conivaptan will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors cortisonecortisone will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Coadministration with duvelisib increases AUC of a sensitive CYP3A4 substrate which may increase the risk of toxicities of these drugs.
- Vardenafil 5 mg may be less effective if taken with high-fat meals.
- Side effects like indigestion or muscle aches are possible.
- Inform your doctor about any allergic reactions experienced.
- Be cautious if you have low blood pressure or heart disease.
- It is recommended to avoid taking other ED medications concurrently.
- Regular check-ups help assess medication effectiveness.
- Discontinue use and seek help if adverse reactions occur.
- The medication can improve intimacy confidence and quality.
- Use the lowest effective dose to minimize side effects.
- Vardenafil 5 mg is generally safe when used responsibly.
- Keep out of reach of children and pets.
- Consult your healthcare provider for personalized advice.
Consider reducing the dose of the sensitive CYP3A4 substrate and monitor for signs of toxicities of the coadministered sensitive CYP3A substrate. duvelisib will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. efavirenzefavirenz will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
See also:
artemether/lumefantrine will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. asenapinevardenafil increases effects of asenapine by pharmacodynamic synergism. vardenafil increases effects of asenapine by pharmacodynamic synergism. atazanaviratazanavir will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Limit vardenafil dose to 2.5 mg/24 hr atomoxetineatomoxetine and vardenafil both increase QTc interval.
Related Disease Conditions
atomoxetine and vardenafil both increase QTc interval. bedaquilinevardenafil and bedaquiline both increase QTc interval. vardenafil and bedaquiline both increase QTc interval. Either increases effects of the other by Mechanism: pharmacodynamic synergism. bicalutamidebicalutamide will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.
Incidence not known
Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors bicalutamide will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Vardenafil dose may need to be reduced if coadministered with moderate or strong CYP3A4 inhibitors bosentanbosentan will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. bosentan will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. budesonidebudesonide will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. budesonide will decrease the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.efavirenz and vardenafil both increase QTc interval.
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